Table 1 Physicochemical properties of produced nanoparticles

Size (nm)

90 ± 1.3

100 ± 4.1

135 ± 1.8

147.9 ± 3.8

PDI

0.25 ± 0.04

0.3 ± 0.04

0.4 ± 0.03

0.29 ± 0.06

Zeta potential (mV)

12.7 ± 2.1

13.5 ± 1.3

12.1 ± 1.3

14.3 ± 1.8

RTX encapsulation efficiency (%)

76.89%

CP encapsulation efficiency (%)

75.67%

siRNA encapsulation efficiency (%)

90%

CP loading capacity (%)

11.6%