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Fig. 9 | Cell Communication and Signaling

Fig. 9

From: Inhibition of ERK downregulates autophagy via mitigating mitochondrial fragmentation to protect SH-SY5Y cells from OGD/R injury

Fig. 9

Inhibition of ERK promotes expression of mitochondrial fusion proteins by increment of Mfn2 after OGD/R in SH-SY5Y cells. A Representative immunoblot bands of mitochondrial fusion proteins: Opa1, Mfn2 and Mfn1; B-D, Quantitative analysis of expression of Opa1, Mfn2 and Mfn1. All data in this figure are representative of three independent repeats and are shown as mean ±SEM. si-Mfn2(C): Mfn2 si-RNA without OGD/R group; PD: PD98059 group; Mfn2: Mfn2 si-RNA group. *P < 0.05 vs. Control, #P < 0.05 vs. Model, &P < 0.05 vs. PD

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