Fig. 4From: Enhancer RNAs: mechanisms in transcriptional regulation and functions in diseaseseRNAs can facilitate RNAPII pause-release to enhance transcription extension. A eRNAs can promote the release of NELF by directly bind to NELF subunit, allowing the RNAPII to effectively transit to a productive transcription extension. B eRNAs can facilitate RNAPII pause-release by binding to P-TEFb complex subunit, activating P-TEFb and promoting RNAPII 2 phosphorylationBack to article page