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Fig. 2 | Cell Communication and Signaling

Fig. 2

From: Communications between macrophages and cardiomyocytes

Fig. 2

Phagocytic Function of Macrophages (Mø). Macrophages phagocytize CM debris. The phagocytic function of macrophages is regulated by Lgmn and Smad3 signaling. In addition, macrophages engulf dysfunctional mitochondria from CMs via MerTK. Similarly, CMs internalize macrophage-derived mitochondria by clathrin- or lipid raft-mediated endocytosis and induce CM injury by triggering ferroptosis

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Cell Communication and Signaling

ISSN: 1478-811X