Fig. 7

First shell interaction network of PRAME as determined by The Search Tool for the Retrieval of Interacting Genes (STRING). A The STRING model confidence was set to medium (0.400). There are 85 nodes in the network with 577 edges (i.e., interactions). The number of interactions was significantly more than the expected 126 interactions in a randomly selected set of proteins of the same size (p-value < 1.0 × 10^–16). B The STRING model confidence was set to high (0.900). There were 4 nodes in the network with 4 edges (interactions). The number of interactions was approximately the same as what was expected for a randomly selected set of proteins of the same size (p-value < 0.337)