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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: ATRA sensitized the response of hepatocellular carcinoma to Sorafenib by downregulation of p21-activated kinase 1

Fig. 1

High levels of PAK1 were correlated with decreased survival of HCC patients. A Gene expression of PAK1 in HCC tissues (369) and normal tissues (160) from the GEPIA dataset was compared using a t-test. Each dot represented a patient. B PAK1 expression in the normal tissue (M-00100) and HCC tissue (M-81703) from the Human Protein Atlas database was determined by IHC. The recurrence-free survival (C) and overall survival (D) of HCC patients were calculated using Kaplan–Meier and Landmark analysis. N, normal tissue; T, tumour (HCC); TPM, Transcripts Per Kilobase of exon model per Million mapped reads

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