Fig. 4
From: PECAM-1 drives β-catenin-mediated EndMT via internalization in colon cancer with diabetes mellitus
β-catenin is a crucial modulator during the process of EndMT in CC with DM. a The interaction of PECAM-1 with β-catenin was assessed through Genemania databases and Co-IP assay. b, c Expressions of total β-catenin were tested by western blotting in cancerous and noncancerous adjacent tissues of CC with and without DM, respectively. d-g Total and nuclear β-catenin were analyzed by western blotting under HG and SNs conditions, respectively. The samples derive from the same experiment and that blots were processed in parallel. Data are means ± S.E.M. and analyzed using unpaired and paired student’s t-test and one-way ANOVA followed by Tukey’s multiple comparisons test. *p < 0.05, **p < 0.01