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Fig. 3 | Cell Communication and Signaling

Fig. 3

From: PECAM-1 drives β-catenin-mediated EndMT via internalization in colon cancer with diabetes mellitus

Fig. 3

Defection of PECAM-1 promoted the EndMT in HUVECs. a PECAM-1 was detected after siRNA treatment by western blotting. b, c EndMT markers were detected PECAM-1 siRNA treatment by western blotting. d Cellular shape was evaluated during EndMT after PECAM-1 siRNA treatment under NG and HG conditions. The samples derive from the same experiment and that blots were processed in parallel. Ctrl: control, NC: negative control, siPECAM-1: PECAM-1 siRNA. Data are means ± S.E.M. and analyzed using one-way ANOVA followed by Tukey’s multiple comparisons test. *p < 0.05, **p < 0.01, ***p < 0.001

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