Fig. 1
From: PECAM-1 drives β-catenin-mediated EndMT via internalization in colon cancer with diabetes mellitus
Diabetes mellitus promotes the progression and TME remodeling in CC. a Clinical characteristic were analyzed between CC patients with DM and without DM and genes on TME biological diversity were detected by human mRNA-microarray, respectively. b, c Vesicle-related genes were determined to link to EMT and/or EndMT through Pearson correlation analysis and GENEMANNIA database. d Volumes of xenograft were assessed in mice with and without DM. CC: colon cancer, DM: diabetes mellitus, MOS: months. Data are analyzed using unpaired student’s t-test and χ2 test. *p < 0.05