Table 2 Role of MSCs derived exosomes from different sources
From: The role of MSCs and CAR-MSCs in cellular immunotherapy
Diseases | MSCs Origin | Response | Ref |
|---|---|---|---|
Alzheimer’s disease | Human adipose tissue Human BM | Adipose MSCs derived exosomes have superior effects compared to BM-MSCs derived exosomes Decreased Aβ peptide in the N2a cells | [73] |
Neurodegenerative disease | Human menstrual tissue Human BM | Promoted neurite outgrowth in cortical and sensory neurons | [75] |
Human chorion Human umbilical cord | No effect | ||
Osteoarthritis (OA) | Human iPSCs Human SM Human BM | Attenuated OA in a murine model Stimulated chondrocyte migration and proliferation iMSCs derived exosomes exert superior therapeutic effects compared to SM-MSCs derived exosomes | [76] |
Glioblastoma | Human BM Human Wharton’s jelly | Decreased the proliferation of U87MG cell Induced apoptosis in the U87MG cells | [74] |
Human adipose tissue | Increased the proliferation of U87MG cell No apoptotic effect |