Table 1 Characteristics of extracellular vesicles
From: The role of MSCs and CAR-MSCs in cellular immunotherapy
| Â | Apoptotic bodies | Microvesicles | Exosomes |
|---|---|---|---|
Origin | Cells undergo apoptosis | Cell’s plasma membrane | Endosomal compartment |
Shape | Irregular | Irregular | Regular |
Size | 50–5000 nM | 100–1000 nM | 30–150 nM |
Markers | Intact organelles, chromatin,histones | Cytoskeletal proteins, heat shock proteins, integrins | CD9, CD63, CD81, Alix, TSG100 |