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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: Non-POU Domain-Containing Octomer-Binding (NONO) protein expression and stability promotes the tumorigenicity and activation of Akt/MAPK/β-catenin pathways in human breast cancer cells

Fig. 1

NONO is significantly expressed in breast cancer. a Expression levels of NONO in different cancers types and their respective normal tissues according to data retrieved from the TIMER database. b TCGA data from UALCAN suggested that NONO expression was significantly higher in breast cancer than in normal breast tissue. c NONO gene expression profile in normal breast tissue, breast tumor and metastatic breast tissue. Using the TNMplot web platform. d Representative IHC image of NONO protein expression in breast cancer tissue and adjacent normal tissue. Scale bar, 50 µm. e Quick score distribution of NONO in breast cancer tissue (n = 20) versus normal tissue (n = 20). f, g According to TCGA data from UALCAN, NONO is significantly overexpressed in different stages and subclasses of breast cancer. *p < 0.05, ***p < 0.001

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Cell Communication and Signaling

ISSN: 1478-811X