Fig. 4
From: Involvement of the SIRT1-NLRP3 pathway in the inflammatory response
The SIRT1-NLRP3 pathway in several inflammation-related diseases. SIRT1-NLRP3 pathway influences the inflammatory response and relates to melatonin, traumatic brain injury, neuroinflammation, depression, atherosclerosis, and liver damage. (Sirt1: Silent information regulator 2 homolog 1; ROS: Reactive oxygen species; NLRP3: NACHT, LRR and PYD domains-containing protein 3; ASC: a protein; IL: Interleukin; TBI: Traumatic brain injury; Nrf2: Nuclear factor erythroid 2-related factor 2)