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Fig. 5 | Cell Communication and Signaling

Fig. 5

From: P38-DAPK1 axis regulated LC3-associated phagocytosis (LAP) of microglia in an in vitro subarachnoid hemorrhage model

Fig. 5

P38-regulated LAP via DAPK1. The protein expression of DAPK1 after SB203580 added (a). Protein bands (b) and semi-quantitative analysis showing the protein expression of DAPK1 (c), LC3 II (c), BECN1 (d) and RUBICON (d) after transfection of DAPK1-specific plasmid. The change of microglial phagocytosis after DAPK1 knock-down (e). The mRNA expression of Il-1β, Il-6 and Nlrp3 after DAPK1 knock-down (f). ****-P < 0.0001, ***-P < 0.001, **-P < 0.01, *-P < 0.05; ns, non-significant

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