Table 2 MrgD KO improved AngII-induced cardiac dysfunction in the mice

LVEF (%)

75.40 ± 2.278

75.34 ± 1.594 ^ns

78.31 ± 2.395

68.13 ± 5.952 ^ns

LVFS (%)

43. 76 ± 2.108

43.17 ± 1.641 ^ns

46.10 ± 2.309

38.12 ± 4.133 ^ns

LV mass (mg)

135.1 ± 6.036

161.9 ± 5.127 ^*

108.3 ± 4.645

139.8 ± 9.153 ^ns

LVIDs (mm)

2.004 ± 0.1009

1.793 ± 0.06207 ^ns

1.786 ± 0.1073

2.116 ± 0.2544 ^ns

LVIDd (mm)

3.551 ± 0.05798

3.162 ± 0.08756 ^*

3.304 ± 0.07619

3.319 ± 0.1373 ^ns

Volume;s (ml)

13.25 ± 1.591

9.831 ± 0.8532 ^ns

9.798 ± 1.460

16.64 ± 5.265 ^ns

Volume;d (ml)

52.88 ± 1.997

40.26 ± 2.743 ^*

44.46 ± 2.464

45.38 ± 4.632 ^ns

LVAW;s (mm)

1.665 ± 0.05349

1.845 ± 0.05388 ^ns

1.533 ± 0.02593

1.630 ± 0.05772 ^#

LVAW;d (mm)

1.102 ± 0.03870

1.285 ± 0.05180 ^*

0.9819 ± 0.03872

1.114 ± 0.02342 ns

LVPW;s (mm)

1.428 ± 0.02349

1.708 ± 0.05019 ^***

1.342 ± 0.05937

1.459 ± 0.04320 ^#

LVPW;d (mm)

0.9150 ± 0.02328

1.253 ± 0.06023 ^****

0.8911 ± 0.01179

1.060 ± 0.05403 ^#

Heart weight (mg)

100.4 ± 1.547

141.2 ± 5.014 ^****

100.3 ± 3.376

118.1 ± 4.179 ^##

Body weight (g)

20.04 ± 0.6955

19.65 ± 0.9044 ^ns

17.94 ± 0.7117

19.55 ± 0.9614 ^ns

Tibia length (mm)

16.00 ± 1.2080

17.81 ± 0.8991 ^ns

17.07 ± 1.283

16.02 ± 0.5746 ^ns