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Table 1 Cardiac function was reduced after MrgD overexpression in the hearts of rat

From: Nuclear import of Mas-related G protein-coupled receptor member D induces pathological cardiac remodeling

Variables

Ad-GFP (n = 6)

Ad-MrgD (n = 6)

LVEF (%)

72.15 ± 0.6543

54.39 ± 1.084***

LVFS (%)

42.57 ± 0.1386

29.33 ± 0.822***

LV mass (mg)

1048.07 ± 15.20

1131.80 ± 20.61*

LVIDs (mm)

4.177 ± 0.1515

5.735 ± 0.2772 ns

LVIDd (mm)

7.274 ± 0.1703

8.116 ± 0.2412*

LVAW;s (mm)

3.208 ± 0.1241

2.780 ± 0.1428*

LVAW;d (mm)

1.809 ± 0.07785

1.819 ± 0.07617 ns

LVPW;s (mm)

3.137 ± 0.09524

2.743 ± 0.07900**

LVPW;d (mm)

2.094 ± 0.1134

1.784 ± 0.06935*

Heart weight (mg)

1063 ± 25.21

1523 ± 63.62****

Body weight (g)

328.3 ± 17.31

302.6 ± 13.49 ns

Tibia length (mm)

48.07 ± 0.3029

48.08 ± 0.2762 ns

  1. Echocardiographic data of mice receiving intra-myocardial injection of Ad-MrgD or GFP. The results are expressed as the mean ± SEM (LVEF Left ventricular ejection fraction, LVFS Left ventricular fractional shortening, LVIDs LV internal diameters at end systole, LVIDd LV internal diameters at end diastole, LVAW;s Left ventricular systolic anterior wall, LVAW;d Left ventricular diastolic anterior wall, LVPW;s Left ventricular systolic posterior wall, LVPW;d Left ventricular diastolic posterior wall)
  2. nsP > 0.05, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001
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Cell Communication and Signaling

ISSN: 1478-811X