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Fig. 7 | Cell Communication and Signaling

Fig. 7

From: Nuclear import of Mas-related G protein-coupled receptor member D induces pathological cardiac remodeling

Fig. 7

Effects of PTX on the protective role of silencing MrgD in Ang II-induced cardiac remodeling. A, HW/BW and HW/TL in the hearts from different groups. B, the mRNA levels of Nppa and Nppb, as well as the ratio of Myh 6/7in the hearts from different groups. C, PTX pretreatment blocked the protective effects of silencing MrgD against Ang II-induced cardiac fibrosis in rats, as indicated by masson and picrosirius red staining. D-E, the protein and mRNA levels of α-SMA, TGF-β and collagen I in the hearts from different groups. The results are expressed as mean ± SEM. n = 3 biological replicates per group. nsP > 0.05, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001

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Cell Communication and Signaling

ISSN: 1478-811X