Fig. 1
From: Cancer stem cell fate determination: mito-nuclear communication
Phenotypic plasticity of cancer stem cells. The plasticity of CSCs is exhibited as the dynamic and reversible transitions between quiescent and proliferative CSCs, epithelial and mesenchymal CSCs and CSCs and non-CSCs (A) or the evolution from primary CSCs to MeCSCs or CRCSCs (B). CSCs Cancer stem cells, MeCSCs Metastatic cancer stem cells, CRCSCs Chemoresistant cancer stem cells