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Fig. 3 | Cell Communication and Signaling

Fig. 3

From: Colonic stem cells from normal tissues adjacent to tumor drive inflammation and fibrosis in colorectal cancer

Fig. 3

Gene expression differences between clones derived from NAT, HLT and tumor tissues. A Bar plots of the enriched GO terms of upregulated genes in CRC tumor tissues compared with HLT. The terms were selected from the top 20 biological process terms, p < 0.001. B Bar plots of the enriched GO terms of upregulated genes in CRC tumor tissues compared with NAT. The terms were selected from the top 20 biological process terms, p < 0.001. C Bar plots of the enriched GO terms of upregulated genes in NAT compared with HLT. The terms were selected from the top 20 biological process terms. D The principal components analysis (PCA) representing the dispersion of the samples based on their gene expression levels. CRC clones (red), NAT clones (green) and HLT clones (blue). E Somatic mutations found in CRC related genes are present in CRC clones but not in NAT clones. Mutation type is indicated in the legend

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Cell Communication and Signaling

ISSN: 1478-811X