Table 9 Intratumoural microbiota that can cooperate with immunotherapy
From: Intratumoural microbiota: from theory to clinical application
Intratumoural microbiota | Mechanism | Cancer | References |
|---|---|---|---|
Bifidobacterium | Local delivery of bifidobacteria effectively stimulates STING signaling and increases crossover initiation of dendritic cells following anti-CD47 treatment, thereby influencing treatment | Colorectal cancer | [20] |
Enterococcus faecalis | Promoting TH1 differentiation of CD4 + T cells and CD8 + T-cell activation | Pancreatic Cancer | [22] |
E. coli Top10 | Induction of tumor-specific CD4 + and CD8 + T cells | Colorectal cancer | [124] |