Table 8 Intratumoural microbiota that can be targeted
From: Intratumoural microbiota: from theory to clinical application
Intratumoural microbiota | Characteristics | Results | References |
|---|---|---|---|
C.butyricum | Capable of spontaneous aggregation within Colorectal cancer tissue | Promising anti-tumor efficacy coupled with relatively low toxicity and adverse effects | [119] |
Clostridium | Colonization and proliferation are limited to anoxic TME | Promising anti-tumor efficacy | [120] |
Salmonella, Escherichia | In the TME with relatively high oxygen content, colonization and proliferation were observed | Promising anti-tumor efficacy | [120] |
Listeria Monocytogenes | Combined with radionuclide 188 rhenium (188Re) to provide radioactivity to pancreatic cancer metastasis | Good anti-tumor effect without serious side effects | [122] |