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Fig. 5 | Cell Communication and Signaling

Fig. 5

From: Microvesicles from bone marrow-derived mesenchymal stem cells promote Helicobacter pylori-associated gastric cancer progression by transferring thrombospondin-2

Fig. 5

Depletion of the THBS2 gene in BMSC-MVs inhibits the proliferation, migration and invasion of MGC-803 cells in vitro. A-C The proliferation of MGC-803 cells cocultured with sh-NC-MVs/sh-THBS2-MVs with or without H. pylori intervention. D-F The migration and invasion of MGC-803 cells cocultured with sh-NC-MVs/sh-THBS2-MVs with or without H. pylori intervention. BMSCs: bone marrow-derived mesenchymal stem cells; MVs: microvesicles; Hp: Helicobacter pylori; GC: gastric cancer; IHC: immunohistochemistry. *P < .05, **P < .01, ***P < .001, NS: no significance

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Cell Communication and Signaling

ISSN: 1478-811X