From: The biological function of tumor-derived extracellular vesicles on metabolism
Type of tumour | Purpose | Details* | |||
---|---|---|---|---|---|
NCT number | Start date | Primary objective of exosome analysis | Phase | ||
Breast Cancer | Biomarker | NCT04781062 | January 19, 2021 | Early detection of breast cancer | - |
NCT05286684 | January 4, 2023 | Diagnosis of metastatic meningitis | - | ||
NCT04288141 | December 20, 2019 | Measure the Expression of the HER2-HER3 Dimer | - | ||
NCT04258735 | July 17, 2019 | Genomic profiling | - | ||
Digestive and gynecological / breast cancers | Biomarker | NCT04530890 | January 20, 2021 | Diagnostic and prognostic biomarkers | - |
Cholangiocarcinoma | Biomarker | NCT03102268 | May 1, 2017 | Exosomes profiling | - |
Hepatocellular Carcinoma | Therapy | NCT05375604 | June 28, 2022 | Macrophage Reprogramming Agent, exoASO-STAT6 (CDK-004) | Phase 1 |
Gallbladder Carcinoma | Biomarker | NCT03581435 | January 1, 2018 | Exosomes profiling | - |
Clear Cell Renal Cell Carcinoma | Biomarker | NCT04053855 | January 29, 2020 | CA9 + and CD9 + exosome analysis | - |
Bladder Cancer | Biomarker | NCT05270174 | June 1, 2023 | Preoperative diagnosis of lymphatic metastasis using urinary exosome lncRNAs | - |
Therapy | NCT05559177 | September 1, 2022 | Chimeric Exosomal Tumor Vaccines | Phase 1 | |
Colorectal Cancer | Biomarker | NCT04394572 | January 7, 2021 | Diagnostic biomarkers | - |
NCT03874559 | February 13, 2018 | Exosomes profiling | - | ||
NCT04523389 | July 1, 2020 | Prognostic biomarkers | - | ||
NCT04227886 | December 1, 2019 | Predictive biomarkers | - | ||
NCT04852653 | September 21, 2021 | Predictive biomarkers | - | ||
Therapy | NCT01294072 | January 2011 | Plant Exosomes combined with curcumin for colon cancer | Phase 1 | |
Gastric Cancer | Biomarker | NCT05334849 | November 1, 2018 | Exosomal lncRNA-GC1 detection | - |
NCT05397548 | May 1, 2022 | Exosomal lncRNA-GC1 detection | - | ||
NCT05427227 | July 1, 2022 | Predictive biomarkers | - | ||
Head and Neck Cancer | Therapy | NCT01668849 | August 2, 2012 | Plant Exosomes to treat oral mucositis | Phase 1 |
Lung Cancer | Biomarker | NCT03542253 | May 20, 2018 | Diagnostic biomarkers | - |
NCT04529915 | April 9, 2020 | Diagnostic biomarkers | - | ||
NCT04939324 | June 21, 2021 | Exosomes molecular Profiling | - | ||
NCT04629079 | October 23, 2020 | Diagnostic biomarkers | - | ||
NCT04323579 | July 1, 2018 | Diagnostic biomarkers | - | ||
NCT03830619 | January 1, 2017 | Diagnostic biomarkers | - | ||
NCT04315753 | January 1, 2018 | Diagnostic biomarkers | - | ||
NCT05218759 | February 21, 2022 | Predictive biomarkers | - | ||
NCT05424029 | June 14, 2022 | Prognostic biomarkers | - | ||
NCT04427475 | June 8, 2020 | Predictive biomarkers | - | ||
NCT03317080 | September 27, 2017 | Prognostic and predictive biomarkers | - | ||
NCT03108677 | May 1, 2017 | Diagnostic and prognostic biomarkers | - | ||
NCT04182893 | October 8, 2019 | Diagnostic biomarkers | - | ||
NCT04499794 | August 1, 2020 | Diagnostic and predictive biomarkers | - | ||
NCT03228277 | July 17, 2017 | Predictive biomarkers | Phase 2 | ||
Therapy | NCT01159288 | May 19, 2010 | Exosomal Tumor Vaccines | Phase 2 | |
Melanoma | Biomarker | NCT02310451 | December 2014 | Exosomes profiling | - |
Non-Hodgkin B-cell Lymphomas | Biomarker | NCT03985696 | July 2, 2019 | Exosomes profiling and diagnostic function | - |
Osteosarcoma | Biomarker | NCT05101655 | October 1, 2020 | Diagnostic and predictive biomarkers | - |
Ovarian Cancer | Biomarker | NCT03738319 | November 10, 2018 | Exosomes profiling | - |
Pancreatic Cancer | Biomarker | NCT03821909 | August 1, 2018 | Exosomes profiling and diagnostic function | - |
NCT02393703 | March 2015 | Exosomes profiling | - | ||
NCT03791073 | January 1, 2018 | Exosomes profiling | - | ||
NCT03032913 | February 15, 2017 | Diagnostic biomarkers | - | ||
NCT04636788 | November 1, 2020 | Diagnostic and prognostic biomarkers | - | ||
NCT05441189 | April 19, 2021 | Prognostic and predictive biomarkers | - | ||
Therapy | NCT03608631 | January 27, 2021 | Mesenchymal Stromal Cells-Derived Exosomes with KrasG12D siRNA | Phase 1 | |
Prostate Cancer | Biomarker | NCT02702856 | May 2014 | Diagnostic biomarkers | - |
NCT04556916 | February 19, 2021 | Diagnostic biomarkers | - | ||
NCT03694483 | October 3, 2018 | Diagnostic biomarkers | - | ||
NCT03236688 | February 2016 | Exosomes profiling | - | ||
NCT04720599 | June 1, 2020 | Diagnostic biomarkers | - | ||
NCT03911999 | May 3, 2018 | Prognostic exosomes | - | ||
Thyroid Cancer | Biomarker | NCT03488134 | August 3, 2018 | Prognostic biomarkers | - |
NCT02862470 | August 5, 2016 | Prognostic biomarkers | - | ||
NCT03109847 | January 5, 2017 | Exosomes profiling | - | ||
NCT05463107 | August 1, 2022 | Diagnostic biomarkers | - | ||
NCT04948437 | August 19, 2021 | Prognostic biomarkers | - | ||
Bone Metastases | Biomarker | NCT03895216 | December 3, 2018 | Prediction of bone metastasis | - |