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Fig. 5 | Cell Communication and Signaling

Fig. 5

From: Serotonin acts through YAP to promote cell proliferation: mechanism and implication in colorectal cancer progression

Fig. 5

5-HT promotes primary colon carcinogenesis in mice. A AOM combined with DSS in indicative groups was used to treat tumour images in the mice’s intestinal tissues. B Tumour numbers in the indicated groups of mice. *, P < 0.05; **, P < 0.01. C Tumour volume in the indicated groups of mice. *, P < 0.05; **, P < 0.01. D Immunohistochemistry was performed to analyse YAP expression in colorectal carcinoma tissues of the indicated group of mice. *, P < 0.05; **, P < 0.01. E ELISA analysis detected the serum of the mice’s indicated group’s contents of 5-HT. *, P < 0.05; **, P < 0.01

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Cell Communication and Signaling

ISSN: 1478-811X