A comprehensive insight into the correlation between ncRNAs and the Wnt/β-catenin signalling pathway in gastric cancer pathogenesis

Table 1 MiRNAs directly target Wnt/β-catenin signaling pathway in GC

MicroRNA	Oncogene/suppressor	Biological functions	Target genes	References
miR-501-5p	Oncogene	Stem cell-like phenotype	DKK1, GSK3β, and NKD1	[58]
miR-493	Oncogene	Proliferation, invasion, and chemo-resistance	DKK1	[60]
miR-532	Oncogene	Migration and invasion	NKD1	[61]
miR-140-5p	Suppressor	Proliferation, invasion	WNT1	[68]
miR-200b	Suppressor	Proliferation, apoptosis	WNT1	[69]
miR-22	Suppressor	Proliferation, apoptosis	WNT1	[69]
miR-491-5p	Suppressor	Proliferation, colony formation, apoptosis	Wnt3a	[70]
miR-192	Oncogene	Proliferation, migration	APC	[62]
miR-215	Oncogene	Proliferation, migration	APC	[62]
miR-106a-3p	Oncogene	EMT and metastasis	APC	[63]
miR-27	Oncogene	EMT	APC	[64]
miR-135b-5p	Oncogene	Proliferation	APC	[65]
miR-BART19-3p	Oncogene	Proliferation	WIF1, APC	[66]
miR-532-3p	Oncogene	Proliferation, EMT, migration	APC	[71]
miR-200a	Suppressor	Viability, invasion, EMT	β-catenin	[67]

ISSN: 1478-811X