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Table 1 Cox regression model for the association between serum ADAM17 and all-cause mortality

From: P38 MAPK activated ADAM17 mediates ACE2 shedding and promotes cardiac remodeling and heart failure after myocardial infarction

 

ADAM17 (pg/ml)

P value

Low (n = 32)

High (n = 44)

No. deaths

6

13

 

Unadjusted

Ref

5.801 (1.936–17.384)

0.002

Model 1

Ref

3.544 (1.119–11.223)

0.031

Model 2

Ref

3.582 (1.128–11.370)

0.030

Model 3

Ref

4.342 (1.271–14.834)

0.019

Model 4

Ref

5.620 (1.406–22.470)

0.015

  1. Unadjusted model adjusted for none. Model 1 is adjusted on age and gender. Model 2 is adjusted on age, gender, co-morbidities (hypertension and diabetes mellitus). Model 3 is adjusted on age, gender, co-morbidities (hypertension and diabetes mellitus), biological variables (NT-proBNP, cTNI, eGFR, hs-CRP, TC and TG). Model 3includes variables of Model 3, treatment (PCI information, β-blockers, ACEIARB, ARNI, and diuretics)
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Cell Communication and Signaling

ISSN: 1478-811X