Fig. 1

High expression of ADAM17 is associated with the occurrence of post-MI HF. A The expression of ADAM17 in peripheral blood of patients was detected by ELISA. B Spearman correlation between ADAM17 expression of peripheral blood and EF% in patients with MI. C Receiver-operating characteristic curve (ROC) for ADAM17 and their corresponding area under the curve (AUC) values. D The post-MI HF patients were divided in two groups according by ADAM17 expression level. Mortality rates were analysed using the Kaplan–Meier method. E Post-MI HF patients was divided into two subgroups by NYHA functional class (I and II vs. III and IV), ADAM17 levels was detected by ELISA in two HF subgroups. F Evolution of serum ADAM17 levels after HF during 1-year follow-up. Data shown as mean ± SEM. *P < 0.05; **P < 0.01, ***P < 0.001