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Fig. 6 | Cell Communication and Signaling

Fig. 6

From: Targeting ER stress/PKA/GSK-3β/β-catenin pathway as a potential novel strategy for hepatitis C virus-infected patients

Fig. 6

Schematic diagram of the ER stress/PKA/GSK-3β-dependent Wnt/β-catenin pathway. A Chronic HCV infection activates ER stress/PKA/GSK-3β-dependent Wnt/β-catenin signaling. B Targeting ER stress/PKA/GSK-3β-dependent Wnt/β-catenin pathway by either PKA or ER stress inhibitor both represses HCV replication and reverses Wnt/β-catenin signaling. C Targeting ER stress/PKA/GSK-3β-dependent Wnt/β-catenin pathway by either PKA or ER stress inhibitor both inhibits extracellular HCV infection, probably through inhibition of viral either entry or replication or both

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Cell Communication and Signaling

ISSN: 1478-811X