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Fig. 4 | Cell Communication and Signaling

Fig. 4

From: Platelet-derived microparticles stimulate the invasiveness of colorectal cancer cells via the p38MAPK-MMP-2/MMP-9 axis

Fig. 4

Activity of metalloproteinases in CRC cells after PMP uptake. A Degradation of FITC-labelled gelatine by CRC cells. B Migration of CRC cells through gelatine-coated Boyden chambers in the absence or presence of MMP-2 or MMP-9 inhibitors (ARP101 or CTK8G1150, respectively). Quantified data (presented and statistically analysed as in Fig. 1) of the percentage of gelatine-migrated cells compared to the control (nontreated cells, 100%, marked with dashed horizontal bars.). **P < 0.01, *P < 0.05, N = 5

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Cell Communication and Signaling

ISSN: 1478-811X