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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: Platelet-derived microparticles stimulate the invasiveness of colorectal cancer cells via the p38MAPK-MMP-2/MMP-9 axis

Fig. 1

The internalization of platelet-derived microparticles by colorectal cancer cells. A 20× and B 100× magnification: representative confocal microscopy images of PKH67-labelled PMPs uptake (green) by HT29, SW480 and SW620 cells during 4 h of incubation. Staining with Hoechst 33,342 (blue) for nuclei and Alexa Fluor 594 (red) wheat germ agglutinin for cell membrane C – flow cytometry analysis of PKH67-labelled PMP internalization. The results are presented as the mean (vertical line) and standard error (box). Significance estimated with the nonparametric U-Man-Whitney test: ***P < 0.001, **P < 0.01, N = 5

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Cell Communication and Signaling

ISSN: 1478-811X