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Fig. 5 | Cell Communication and Signaling

Fig. 5

From: Multiomics analysis revealed the mechanisms related to the enhancement of proliferation, metastasis and EGFR-TKI resistance in EGFR-mutant LUAD with ARID1A deficiency

Fig. 5

The enhancement of metastasis in ARID1A knockdown EGFR-mutant lung adenocarcinoma is a process involving multiple factors and multiple mechanisms. A–D Proteins enriched in metastasis-related pathways revealed by mass spectrometry (all listed proteins were upregulated in ARID1A knockdown cells with statistical significance). E Relative expression levels of phosphorylated ErbB family members. F Relative expression level of phosphorylated RAF1. G Relative expression level of phosphorylated AKT2. H Relative expression levels of phosphorylated proteins belonging to the MAPK pathway. I Relative expression levels of phosphorylated metastasis-related proteins and EMT biomarkers

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Cell Communication and Signaling

ISSN: 1478-811X