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Fig. 2 | Cell Communication and Signaling

Fig. 2

From: KCNJ2/HIF1α positive-feedback loop promotes the metastasis of osteosarcoma

Fig. 2

KCNJ2-inhibition represses the metastasis of OS cells. A Quantitative real-time polymerase chain reaction (qRT-PCR) was used to detect the mRNA levels of KCNJ2 after transfection of sh1-KCNJ2 and sh2-KCNJ2. B, C Western blotting was used to detect the protein levels of KCNJ2 after transfection of sh1-KCNJ2 and sh2-KCNJ2, respectively. D, E Wound healing assays were used to detect the migration rate of OS cells after KCNJ2-inhibition. F, G Transwell assays were used to detect the invasion rate of OS cells after KCNJ2-inhibition. H, I Lung metastasis model was used to detect the metastasis of 143B cells in vivo after KCNJ2-inhibition. **, P < 0.01

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