Fig. 1
From: KCNJ2/HIF1α positive-feedback loop promotes the metastasis of osteosarcoma
KCNJ2 expression is associated with metastasis in osteosarcoma (OS). A Differentially expressed genes (DEGs) between OS cells with high and low metastatic ability in the GSE18947 cohort. B Differentially expressed genes (DEGs) between OS cells with high metastatic ability and low metastatic ability in the GSE49003 cohort. C Overlapped genes in two cohorts. D Change-fold and P value of overlapped DEGs. E Expression of KCNJ2 in OS tissues provided by patients diagnosed with stage I–II or stage III OS. F Kaplan–Meier survival analysis for OS patients with high and low KCNJ2 expression. G, H The protein levels of KCNJ2 in normal cells (hFOB1.19 and BMSC), OS cells with strong metastatic ability (KHOS, MNNG/HOS, SJSA-1, and 143B) and OS cells with low metastatic ability (MG63, Saos2, U2OS, and HOS). *, P < 0.05; **, P < 0.01