Fig. 5
From: FUT2 inhibits the EMT and metastasis of colorectal cancer by increasing LRP1 fucosylation
1.2- fucosylated glycoproteins reveals regulators of EMT and metastasis. A GO enrichment analysis of N-fucosylated proteins in WT and Fut2△IEC mice based on biological processes. B GO enrichment analysis (category of functional categories) of N-fucosylated proteins in WT and Fut2△IEC mice. C Validation of 1,2 fucosylation in proteins bound with UEA-I related to migration in SW480 cells. D Validation of 1,2 fucosylation in proteins bound with UEA-I related to migration in HCT116 cells. E IP of LRP1 from cell lysates of SW480 cells transduced with LV-FUT2 or LV-NC. F IP of LRP1 from cell lysates of HCT116 cells transduced with LV-FUT2 or LV-NC. G LRP1 immunoprecipitation from cell lysates of HCT116 cells transfected with LV-FUT2 or LV-NC. Anti-LRP1 immunoprecipitates were treated with or without SGN-2FF and blotted with UEA-I or α-LRP1.