Fig. 4
From: FUT2 inhibits the EMT and metastasis of colorectal cancer by increasing LRP1 fucosylation
FUT2 knock-out mice develop AMO and DSS-induced tumors. A FUT2 levels in colon lysates of WT mice and FUT2 knock-out mice were detected by qRT-PCR. B Representative images of UEA-I lectin fluorescence staining revealed α-1,2 fucosylation in WT mice and Fut2△IEC mice. C Representative images of H&E-stained colon sections after AMO and DSS administered. D–E Quantification of C. *p < 0.05. **p < 0.01. F Representative images of IHC staining with N-cadherin and E-cadherin in colon lysates in colon sections in WT mice and FUT2 knock-out mice after AMO and DSS administered. G FUT2 knock-out increased N-cadherin and vimentin, as shown by Western blotting