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Fig. 3 | Cell Communication and Signaling

Fig. 3

From: Targeting and regulation of autophagy in hepatocellular carcinoma: revisiting the molecular interactions and mechanisms for new therapy approaches

Fig. 3

Targeting autophagy to regulate the survival rate of HCC cells. PD-L1 is involved in the process of immunosuppression, while autophagy inhibits PD-L1 in enhancing cancer immunity in HCC. More importantly, pro-survival autophagy can lead to the activation of Wnt signaling by mediating the nuclear translocation of β-catenin, which induces glycolysis and promotes HCC progression

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