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Fig. 3 | Cell Communication and Signaling

Fig. 3

From: Estrogen downregulates CD73/adenosine axis hyperactivity via adaptive modulation PI3K/Akt signaling to prevent myocarditis and arrhythmias during chronic catecholamines stress

Fig. 3

Analysis the effect of E2 on myocardial inflammatory responses during CCS. A–C Expressions of inflammatory markers IL-6, TNFα, and IL-10 were assessed by ELISA (n = 4–6 hearts per group). D–G Representative immunohistochemical staining and graphical presentation of macrophage CD86 and CD206-positive cells assessed from the myocardial sections (n = 4 hearts per group). Data are presented as mean ± SEM; ***p < 0.001; **p < 0.01; *p < 0.05

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Cell Communication and Signaling

ISSN: 1478-811X