Fig. 1From: Estrogen downregulates CD73/adenosine axis hyperactivity via adaptive modulation PI3K/Akt signaling to prevent myocarditis and arrhythmias during chronic catecholamines stressMorphometric and myocardial injury indexes change After 14 days of CCS. A–C Graphical presentations of morphometric data demonstrate alterations in ratio of body weight/heart weight (HW/BW), body weight (BW), and heart weight HW (n = 5–6). D, E Effect of E2 on plasma BNP and ANP concentration (n = 5–6). F, G Representative microscopic images of wheat germ agglutinin (WGA) and graphical illustration of measured cardiomyocyte area. H–M Representative electrocardiography (ECG) and graphical presentation of ECG parameters including; Heart Rate, QT, corrected QT (QTc), JT Interval, and ST Height (n = 5 mice per group). One-way ANOVA, followed by Turkey’s multiple comparison test. ***p < 0.001; **p < 0.01; *p < 0.05).Back to article page