Table 1 Association of WWP2 levels with clinical and pathological features of GC patients
Variables | N | Tumor WWP2 expression | P value | |
|---|---|---|---|---|
WWP2High (%) | WWP2Low (%) | |||
Age (years) | ||||
  < 65 | 66 | 38(57.6) | 28(42.4) | 0.567 |
  ≥ 65 | 64 | 40(62.5) | 24(37.5) | |
Gender | ||||
  Male | 75 | 43(57.3) | 32(42.7) | 0.469 |
  Female | 55 | 35(63.6) | 20(36.4) | |
Tumor size (cm) | ||||
  < 5 | 51 | 28(54.9) | 23(45.1) | 0.340 |
  ≥ 5 | 79 | 50(63.3) | 29(36.7) | |
Differentiation | ||||
  Well or Moderately | 68 | 37(54.4) | 31(45.6) | 0.173 |
  Poor | 62 | 41(66.1) | 21(33.9) | |
TNM stage | ||||
  I-II | 57 | 27(47.4) | 30(52.6) | 0.009 |
  III-IV | 73 | 51(69.9) | 22(30.1) | |
Depth of invasion | ||||
  T1-T2 | 54 | 25(46.3) | 29(53.7) | 0.007 |
  T3-T4 | 76 | 53(69.7) | 23(30.3) | |
Tumor location | ||||
  Proximal | 59 | 34(57.6) | 25(42.4) | 0.615 |
  Distal | 71 | 44(62.0) | 27(38.0) | |
Lauren classification | ||||
  Intestinal type | 65 | 35(53.8) | 30(46.2) | 0.152 |
  Diffuse type | 65 | 43(66.2) | 22(33.8) | |
Lymph node metastasis | ||||
  N0 | 60 | 30(50.0) | 30(50.0) | 0.031 |
  Nx | 70 | 48(68.6) | 22(31.4) | |