Skip to main content
Fig. 8 | Cell Communication and Signaling

Fig. 8

From: WWP2 drives the progression of gastric cancer by facilitating the ubiquitination and degradation of LATS1 protein

Fig. 8

Schematic diagram depicting the mechanism of WWP2-mediated GC progression via LATS1 ubiquitination and subsequent destruction. WWP2 upregulation contributes to the promotion of cell proliferation, migration and invasion of GC cells. WWP2 triggers GC tumorigenesis and progression by facilitating LATS1 ubiquitination and degradation, thereby inducing YAP1 activation

Back to article page

Cell Communication and Signaling

ISSN: 1478-811X