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Fig. 7 | Cell Communication and Signaling

Fig. 7

From: WWP2 drives the progression of gastric cancer by facilitating the ubiquitination and degradation of LATS1 protein

Fig. 7

WWP2 attenuation impedes the growth of GC cells in vivo. A Growth curves of xenograft tumors extracted from BGC-823 cells transfected with scramble shRNA or WWP2 shRNA-1. B, C Images of xenograft tumors were collected, photographed and weighed at the end of the in vivo experiments. D The protein expression of WWP2, LATS1 and YAP1 in xenograft tumors was detected utilizing western blotting assays. E qRT‒PCR experiments were performed to analyze the mRNA levels of WWP2, LATS1 and CTGF in xenograft tumors. The data are summarized as the mean ± SD of three independent experiments. **P < 0.01 by two-tailed t test, n.s indicates no significance

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Cell Communication and Signaling

ISSN: 1478-811X