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Fig. 3 | Cell Communication and Signaling

Fig. 3

From: WWP2 drives the progression of gastric cancer by facilitating the ubiquitination and degradation of LATS1 protein

Fig. 3

WWP2 overexpression triggers the proliferation, migration and invasion of GC cells. A, B The transfection efficiency of the WWP2 expression plasmid was detected by western blotting and qRT‒PCR assays in HGC-27 and SGC-7901 cells. C CCK-8 experiments were performed to analyze cell viability. D, E Colony formation experiments to analyze the effects of overexpression of WWP2 on colony formation ability. F, G Transwell invasion assays of gastric cancer cells transfected with HA-WWP2 or vector. H, I Wound healing assays were performed to evaluate the migration abilities in GC cells upon WWP2 upregulation. Student’s t test: *p < 0.05, **p < 0.01

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Cell Communication and Signaling

ISSN: 1478-811X