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Fig. 3 | Cell Communication and Signaling

Fig. 3

From: SARS-CoV-2 spike protein promotes inflammatory cytokine activation and aggravates rheumatoid arthritis

Fig. 3

Effects of SARS-CoV-2 spike protein on the development and progression of RA. Joint tissues were collected from Control and Spike groups for histological analysis. A Representative images show joint tissues of mice in the Control and Spike groups stained with hematoxylin and eosin (H&E). Bar graphs show joint erosion and inflammation scores. Scale bar = 100 μm (B) IL-1β, TNF-α, IL-17, and MCP-1 expression in the synovium were assessed by immunohistochemistry. Bar graphs show percentages of cells labeled with each antibody. Scale bar = 100 μm, Data are shown as the mean ± SEM. *P < 0.05 (unpaired/two-tailed t test)

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