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Fig. 3 | Cell Communication and Signaling

Fig. 3

From: The mitochondrial Ahi1/GR participates the regulation on mtDNA copy numbers and brain ATP levels and modulates depressive behaviors in mice

Fig. 3

The reduction in mitochondrial Ahi1/GR caused an increase in mtDNA copy numbers. The mtDNA copy numbers in the hypothalamus (HY) and the blood from control mice and Ahi1 KO mice were detected by qPCR. N = 6 mice (a, b). PC12 cells were transfected with Ahi1-siRNA for 48 h, and the mtDNA copy number was detected by qPCR. N = 6 cell samples (c). PC12 cells were treated with Dex (20 μM) for 72 h, and the mtDNA copy number was detected by qPCR. N = 6 cell samples (d). **P < 0.01, ***P < 0.001

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Cell Communication and Signaling

ISSN: 1478-811X