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Fig. 4 | Cell Communication and Signaling

Fig. 4

From: Regulation of the integrin αVβ3- actin filaments axis in early osteogenic differentiation of human mesenchymal stem cells under cyclic tensile stress

Fig. 4

Actin filaments regulated early stage of osteogenic differentiation induced by CTS via integrin αVβ3 activation in MSCs. a Protein and mRNA expression of β-actin under CTS for 4 and 7 days. b Protein and mRNA expression of β-actin under CTS in the CTS and RGDyk groups. c Immunofluorescence of F-actin under CTS in the GM, CTS, and RGDyk groups for 7 days. Scale bar, 20 μm. d Protein expression of ALP and RUNX2 under CTS in the GM and CytoD groups. (Symbol meaning in each statistical graph: Vertical Lines represents the average of three groups of data; Error Bars represents standard deviation; * represents P < 0.05, ** represents P < 0.01. All statistical analyses were performed between the experimental group and control group.)

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Cell Communication and Signaling

ISSN: 1478-811X