Lower SLC7A2 expression is associated with enhanced multidrug resistance, less immune infiltrates and worse prognosis of NSCLC

Table 1 The correlation between SLC7A2 and immune cell markers

Description	Gene	LUAD		LUSC
Description	Gene	Correlation	p	Correlation	p
	CCR7	− 0.012	ns	0.289	***
	CEACAM8	− 0.04	ns	0.023	ns
	ITGAM	− 0.27	***	0.341	***
	KIR2DL1	0.131	***	0.119	***
	KIR2DL3	0.073	ns	0.138	***
	KIR2DL4	0.075	ns	0.112	***
	KIR2DS4	0.051	ns	0.205	***
	KIR3DL1	0.04	ns	0.218	***
	KIR3DL2	0.037	ns	0.167	***
	KIR3DL3	0.058	ns	0.082	ns
	CCL2	− 0.22	***	0.325	***
	CD163	− 0.116	***	0.271	***
	CD68	− 0.17	***	0.179	***
	CD86	− 0.247	***	0.275	***
	CSF1R	− 0.244	***	0.318	***
	IL-10	− 0.176	***	0.194	***
	IRF5	− 0.369	***	− 0.047	ns
	MS4A4A	− 0.196	***	0.235	***
	NOS2	0.072	ns	0.064	ns
	PTGS2	0.115	***	0.279	***
	VSIG4	− 0.255	***	0.208	***
	CD1C	− 0.185	***	0.233	***
	HLA-DPA1	− 0.277	***	0.34	***
	HLA-DPB1	− 0.268	***	0.352	***
	HLA-DQB1	− 0.259	***	0.237	***
	HLA-DRA	− 0.311	***	0.327	***
	ITGAX	− 0.15	***	0.319	***
	NRP1	− 0.039	ns	0.25	***

ISSN: 1478-811X