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Fig. 6 | Cell Communication and Signaling

Fig. 6

From: Lower SLC7A2 expression is associated with enhanced multidrug resistance, less immune infiltrates and worse prognosis of NSCLC

Fig. 6

Lower SLC7A2 expression is associated with worse RFS in NSCLC. A SLC7A2 mRNA transcripts were down-regulated in various cancers of TCGA in the TIMER database. B Tissue specimens were from one patient (magnification, left: × 100 and right: × 400). C The percentage of SLC7A2 expression in NSCLC tissue: -, the staining index score < 2; + , 3 < the score < 5; +  + , 6 < the score < 8; +  +  + , 9 < the score < 12. D RT-qPCR analysis of the relative levels of SLC7A2 mRNA transcripts in the indicated cell lines. E The 427 higher SLC7A2 and 66 lower SLC7A2 expression patients’ prognostic information of Fig. 6A from TCGA database were collected and compared by K–M method of “survival” in R package. Lower SLC7A2 expression group showed poorer prognosis. F–H Lower SLC7A2 expression was associated with worse RFS of LUAD (GSE31210) or NSCLC (GSE8894)

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Cell Communication and Signaling

ISSN: 1478-811X