Table 3 Mimetic peptides that target connexins (Cxs)
From: The roles of connexins and gap junctions in the progression of cancer
Cx target | Peptide | Sequence | Location |
|---|---|---|---|
Cx43 | Gap26 [212] | VCYDKSFPISHVR | EL1 |
| Â | Gap27 [226] | SRPTEKTIFII | EL2 |
| Â | Gap36 [227] | KRDPCHQVDCFLSRPTEK | EL2 |
| Â | Peptide 5 [228] | VDCFLSRPTEKT | EL2 |
| Â | Gap19 [229] | KQIEIKKFK | Cytoplasmic loop |
| Â | L2 [230] | Â | Cytoplasmic loop |
|  | Cx43 266–283 |  | Carboxy terminal |
| Â | ACT1 | Â | Carboxy terminal |
Cx32 | Gap27 [231] | SRPTEKTVFT | EL2 |
| Â | Des5 [227] | LEGHGDPLHLEEC | Cytoplasmic loop |
| Â | Gap24 [232] | GHGDPLHLEEVKC | Cytoplasmic loop |
Cx40 | Gap27 [233] | SRPTEKNVFIV | EL2 |