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Table 2 The effect of Cxs regulation on EMT-related protein expression in different cancers

From: The roles of connexins and gap junctions in the progression of cancer

Cancer

Cx

Cell line

EMT

References

Breast carcinoma

Cx32

MDA-MB-231

promote

[174]

  

Hs578T

inhibit

[175]

 

Cx43

MDA-MB-231, T47D

inhibit

[86, 176]

 

Cx46

MCF-7

promote

[177]

Pulmonary carcinoma

Cx26

HCC827, PC9

promote

[173]

 

Cx31.1

H1299

inhibit

[170]

 

Cx43

A549

inhibit

[171]

Hepatocellular carcinoma

Cx32

HepG2, SMMC-7721

inhibit

[178, 179]