Fig. 2
From: Neuromedin U secreted by colorectal cancer cells promotes a tumour-supporting microenvironment
Expression of tumour microenvironment cell markers in human CRC tissues—TCGA data analysis. Ordered patient data were divided into NMUR1 low (n = 311) and NMUR1 high (n = 310) expression groups according to the median values. RNA expression levels of cell surface markers of a macrophages—CD68, M1 macrophage subtype—CD80 and M2 macrophage subtype—CD163 and CD206; b endothelial cells—CD34, vWF, CLEC14a; and c platelets—GP1BA were analysed in the groups. The boxes represent the interquartile ranges, the horizontal lines in the boxes represent the medians, and the whiskers represent the minimum and maximum values (a CD68 and CD163 and b, c unpaired t test with Welch’s correction, two-tailed, ****p < 0.0001; a CD80 and CD206 Mann–Whitney test, two-tailed, ***p < 0.001, ****p < 0.0001)